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이은희
(Eun-Hee Lee)
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Professor: Eun-Hee Lee, Ph. D.
- Laboratory of pharmaceutical sciences
- Tel: +82-44-860-1620 (office), +82-44-860-1636 (lab)
- Fax: +82-44-860-1606
- E-mail: eunheelee@korea.ac.kr
- Address: 2511 Sejong-ro, Sejong South Korea 30019
Education
| Institution | Degree | Year | Field of Study |
|---|---|---|---|
| Sookmyung Women’s University, South Korea | B.S | 1998 | Pharmacy |
| Sookmyung Women’s University, South Korea | M.S. | 2000 | Pharmaceutics |
| Purdue University, USA | Ph. D | 2007 | Industrial and Physical Pharmacy |
Positions and Employment
| Institution | Years | Position |
|---|---|---|
| Keunsarang Drug Store | 2000 | Pharmacist |
| LG Life Sciences | 2001-2002 | CRA(Clinical Research Associate) |
| Purdue University | 2007-2010 | Postdoctoral Associate |
| College of Pharmacy, Korea Univ. | 2011-present | Assistant Professor |
| Korean Association of Pharmacy Education | 2014-present | Communications Committee member |
| Women’s Bioscience Forum | 2014-present | Marketing Committee member |
| The Korea Society of Food, Drug, and Cosmetics Regulatory Sciences | 2014-present | Scientific Program Committee member |
| The Pharmaceutical Society of Korea | 2015-present | Associate Editor |
| The Pharmaceutical Society of Korea | 2015-present | R&D Committee member |
| The Korean Society of Pharmaceutical Sciences and Technology | 2012-2012 | Finance committee member |
| The Korean Society of Pharmaceutical Sciences and Technology | 2013-2014 | Communications Committee member |
| The Korean Society of Pharmaceutical Sciences and Technology | 2012-2014 | Associate Editor |
| The Korean Society of Pharmaceutical Sciences and Technology | 2015-present | Marketing Committee member |
| The Korean Society of Pharmaceutical Sciences and Technology | 2015-present | Scientific Program Committee member |
주요연구분야
- Polymorph screening, salt screening, cocrystal screening
- Solid State Characterization and Crystallization
- Polymorphs, nano-emulsion, cocrystals, and amorphous (solid dispersion)
- Solubilization of poorly soluble drugs
- Phase transition and Physical Stability
- Process Analytical Technology (PAT) using Raman Spectroscopy with chemometric analysis & Quality by Design
발표논문(2013년 이후 주요 논문)
- 2019 - Ji-Hun An, Alice Nguvoko Kiyonga, Eun Hee Lee, Kiwon Jung. Simple and Efficient Spherical Crystallization of Clopidogrel Bisulfate Form-I via Anti-Solvent Crystallization Method. Crystals. 9, 53 (2019)
- 2018 - Hasanul Banna, Nurhasni Hasan, Juho Lee, Jihyun Kim, Jiafu Cao, Eun Hee Lee, Hyung Ryong Moon, Hae Young Chung, Jin-Wook Yoo. In vitro and in vivo evaluation of MHY908-loaded nanostructure lipid carriers for the topical treatment of hyperpigmentation. J. Drug Deliv. Sci. Tec. 48, 457-465 (2018)
- 2018 - Shwe Phyu Hlaing, Jihyun Kim, Juho Lee, Nurhasni Hasan, Jiafu Cao, Muhammad Naeem, Eun Hee Lee, Jaeh Ho Shin, Yunjin Jung, Bok-Leul Lee, Byung Hak Jhun, Jin-Wook Yoo, S-Nitrosoglutathione loaded poly(lactic-co-glycolic acid) microparticles for prolonge nitric oxide release and enhanced haling of methicillin-resistant Staphylococcus aureus-infected wounds. Eur. J. Pharm. Biopharm. 132, 94-102 (2018)
Bernie Byunghoon Park, NaHye Lee, YunHye Kim, YoonGyu Jae, Seunghyun Choi, NaNa Kang, Yu Ri Hong, - 2017 - Kiwon Ok, Jeonghee Cho, Young Ho Jeon, EunHeeLee, Youngjoo Byun, and JaeHyung Koo. Analogues of Dehydroacetic Acid as Selective and Potent Agonists of an Ectopic Odorant Receptor through a Combination of Hydrophilic and Hydrophobic Interactions. ChemMedChem. 12, 1-7 (2017)
- 2016 - Bishal Raj Adhikari, Daeyoung Kim, Jae Ho Bae, Jisun Yeon, Roshan KC, Sung Kwon Kang, EunHeeLee. New Category for Active Pharmaceutical Ingredients, A Low Molecular Weight Organogelator – Crystal Structure of Atorvastatin Calcium & its Unusual Phase Transition Behavior during Dissolution. Cryst. Growth & Des. 16, 7198-7204 (2016)
- 2016 - Jin-Ki Noha, Muhammad Naeema, Jiafu Cao, EunHeeLee, Min-Soo Kim, Yunjin Jung, Jin-Wook Yoo. Herceptin-functionalized pure paclitaxel nanocrystals for enhanced delivery to HER2-postive breast cancer cells. Int. J. Pharm. 513, 543-553 (2016)
- 2016 - Yeojin Park, Stephan X. M. Boerrigter, Jisun Yeon, Sun Hye Lee, Sung Kwon Kang, EunHeeLee. New Metastable Packing Polymorph of Donepezil Grown on Stable Polymorph Substrates. Cryst. Growth & Des. 16, 2552-2560 (2016) Changkyu Lee, Jisoo Seo, Ha Shin Hwang, Le Quang Thao, Seunghyun Lee, Eun Seong Lee, Eun Hee Lee, Han-Gon Choi, Yu Seok Youn. Treatment of bleomycin-induced pulmonary fibrosis by inhaled tacrolimus-loaded chitosan-coated poly(lactic-co-glycolic acid) nanoparticles. Biomed. Pharmacothera. 78, 226-233 (2016)
- 2015 - Sun Hye Lee, Jaeho Bae, Yeojin Park, Chen Mao, Daeyoung Kim, Kyung Im Kim, Sung Kwon Kang, Eun Hee Lee. Sulfonic Acid Salts of Donepezil & Stabilization of Amorphous Donepezil via Formation of Amorphous Salts. Cryst. Growth & Des. 15, 3123-3130 (2015)
- 2015 - Jiafu Cao, Muhammad Naeem, Jun-Ki Noh, Eun Hee Lee, Jin-Wook Yoo. Dexamethasone Phosphate-Loaded Folate-Conjugated Polymeric Nanoparticles for Selective Delivery to Activated Macrophages and Suppression of Inflammatory Responses. Macromol. Res. 23(5): 485-492 (2015)
- 2015 - Naewon Kang, Jangmi Lee, Ji Na Choi, Chen Mao, and Eun Hee Lee. Cryomilling-induced solid dispersion of poor glass forming/poorly water-soluble mefenamic acid with polyvinylpyrrolidone K12. Drug Dev. Ind. Pharm. 41(6): 978-988 (2015)
- 2014 - Seungyun Choi, YunHye Kim, Bernie Byeonghoon Park, Suzie Park, Jonghyun Park, Kiwon Ok, Jaehyung Koo, Yong Woo Jung, Young Ho Jeon, Eun Hee Lee, Ken S. Lee, Youngjoo Byun. X-ray diffraction and VT-NMR studies of (E)-3-(piperidinyl)-1-(2’-hydroxyphenyl)-prop-2-en-1-one. J. Mol. Struc. 1076:600-605 (2014)
- 2014 - Kyong Hoon Kim, Seung-min Yeon, Hyun Gyung Kim, Hyun Suk Choi, Hyojeung Kang, Hee-Deung Park, Tae Won Park, Seung Pil Pack, Eun Hee Lee, Youngjoo Byun, Sang-Eun Choi, Kenneth Sung Lee, Un-Hwan Ha, and Yong Woo Jung, Diverse Influences of Anderogen-Disrupting Chemicals on Immune Responses Mounted by Macrophages. Inflammation. 37:649-656 (2014)
- 2014 - Eun Hee Lee. 의약품 결정형 평가의 중요성. 대한민국 약전포럼 11권 1호 058-066 (2014)
- 2014 - Eun Hee Lee . A Practical Guide to Pharmaceutical Polymorph Screening & Selection. Asian J. Pharm. Sci. 9:163-175 (2014)
- 2014 - Nam Ah Ki, Du Hyung Choi, Jun Yeul Lim, Ki Hyun Kim, Dae Gon Lim, Eun Hee Lee, Eun-Seok Park, Sejong Hoon Jeong. Investigation of polymeric excipients for dutasteride solid dispersion and its physicochemical characterization. Arch. Pharm. Res. 37:214-224 (2014)
- 2013 - Yeojin Park, Jangmi Lee, Sun Hye Lee, Hoo Gyun Choi, Chen Mao, Sung Kwon Kang, Sand-Eun Choi, and Eun Hee Lee. Crystal Structures of Tetramorphic Forms of Donepezil and Energy/Temperature Phase Diagram via Direct Heat Capacity Measurements. Cryst. Growth & Des. 13:5450-5458 (2013)
- 2013 - Jangmi Lee, Suzie Park, Seon-Joo Yoon, Yong Woo Jung, Youngjoo Byun, Soon Hong Yuk, Min Keyong Jeon, Sung Kwon Kang, and Eun Hee Lee. Multicomponent System of NPS-1034, an Orally Administered Lung Cancer Drug Candidate, with Sulfonic Acids and Solid state Characterzation. Cryst. Growth & Des. 13:3958-3968 (2013)
- 2013 - Jangmi Lee, Stephan X. M. Boerrigter, Yong Woo Jung, Youngjoo Byun, Soon Hong Yuk, Stephen R. Byrn, Eun Hee Lee. Organic Vapor Sortion method of isostructural solvates and polymorph of tenofovir disoproxil fumarate. European J. Pharm. Sci. 50:253-262 (2013)
- 2013 - Hyun Gyung Kim, Sang-Hyun Jo, Seung-min Yeon, Kyong Hoon Kim, Jin Woong Chung, Tae Won Park, Youngjoo Byun, Eun Hee Lee, Young In Park, and Yong Woo Jung. Pluronic Nanoparticles do not Modulate Immune Responses Mounted by Macrophages. Macromol. Res. 21:1355-1359 (2013)
- 2013 - Jianbo Chen, Xitao Yan, Kyung Tae Kim, Sang Hyuck Kim, Eun-Sil Lee, Young Keun Lee, Chang Gyu Son, Eun Hee Lee, Yong Ki Park, Cheong Weon Cho, Young Ho Kim, Youngjoo Byun, and Jong Seong Kang. Comparative Pharmacokinetics of Berberine After Oral Administration of Pure Berberine, Coptidis Rhizoma Extract, and Decoctions of Two Different Complex Herbal Formulas to Rats. Bull. Korean Chem. Soc. 34:1559-1562 (2013)
- 2013 - Keun Sang Oh, Hwanbum Lee, Jae Yeon Kim, Eun Jin Koo, Eun Hee Lee, Jae Hyung Park, Sang Yoon Kim, Kwangmeyung Kim, Ick Chan Kwon, and S. H. Yuk. The multilayer nanoparticles formed by layer by layer approach for cancer-targeting therapy. J. Contoll. Rel. 165: 9-15 (2013)